Application of neural stem cells and mouse models in neuroscience
Supported by:
- The International Centre for Genetic Engineering and Biotechnology
- Central European Initiative
Local organizer and Workshop coordinator:
- Prof. Dinko Mitrečić, MD, PhD / Laboratory for Stem Cells / Croatian Brain Council
T he main goal of the workshop is to cover a broad spectrum ranging from isolation of stem cells, their transplantation to analyses. The workshop will cover theoretical and practical elements of:
- Regenerative potential of neural stem cells
- Mouse models for stroke, neural lesion and neurodegenerative diseases
- Transplantation of stem cells using stereotaxy
- Microscopy in neuroscience
- Bioluminescence in neuroscience
Program:
Lectures and seminars:
- Dinko Mitrečić, Laboratory for stem cells, School of Medicine, University of Zagreb, Croatia
Application of stem cells in brain diseases: current concepts and perspectives - Željka Krsnik, Neurobiology Department, School of Medicine, Yale University, USA
Development of the human cerebral cortex - Emanuele Buratti, Molecular Pathology Group, ICGEB, Trieste, Italy
From cellular to animal models of TAR DNA Binding Protein 43 (TDP-43) aggregation - Darko Bosnakovski, Faculty of Medical Sciences, University Goce Delcev, Stip, FYR Macedonia
Understanding the molecular mechanism of neuromuscular diseases using gene inducible system-in vitro and in vivo models for FSHD - Charles Nicaise, Department of Pathology, Erasme Hospital, Université Libre de Bruxelles, Belgium
Cervical spinal cord injuries: clinically-relevant animal models and experimental therapies targeting glutamate excitotoxicity
Half-day practical hands-on sessions
- Regenerative potential of neural stem cells (stem cell cultures)
- Mouse models for stroke (middle carotid artery occlusion model)
- Transplantation of stem cells using stereotaxy (stereotaxy surgical session)
- Microscopy in neuroscience (confocal/electron microscope session)
Poster session and round tables
Special seminar on bioluminescence with hands on session supported by Perkin Elmer